Preparation and characterization of fluorapatite-bioactive glass S53P4 nanocomposite

Authors

  • Faranak Orand Department of Material Engineering, Yazd Branch, Islamic Azad University, Yazd, Iran
  • Fatemeh Mirjalili Department of Material Engineering, Maybod Branch, Islamic Azad University, Maybod, Iran
  • Mahmood Hajisafari Department of Material Engineering, Yazd Branch, Islamic Azad University, Yazd, Iran
  • Sahebali Manafi Department of Engineering, Shahrood Branch, Islamic Azad University, Shahrood, Iran
Abstract:

This research has been done to study characteristic and biocompatible evaluation of a nano-biocompositeceramic with the bioglass (BG) as a first phase. In this regard, synthesis of S53P4 (53% SiO2, 4% P2O5,23% Na2O and 20% CaO) bioglass has been considered as the first phase and flourapatite (FA) consideredas the second phase. Afterwards, nanocomposite with the base of S53P4 bioglass has been synthesizedby sol-gel method. The synthesized nanoparticles and nanocomposite have been characterized with thehelp of different techniques, using field emission scanning electron microscope (FESEM), X-ray diffraction(XRD), Fourier transforms infrared spectroscopy (FT-IR), X-ray fluorescence (XRF) to evaluate crystalstructure, microstructure, and morphology. The results showed that the crystallite size and the crystallinityof S53P4 bioglass-fluorapatite nanocomposites were about 20-30 nm and 70-90%, respectively.The FT-IR analyses displayed that the purity in the structure of this nanocomposite. The result of MTT(3-(4,5-Dimethylthiazol-2-Yl)-2,5-Diphenyltetrazolium Bromide) assay indicated the nontoxicity and alsodecreasing of cell viability in 7 days compared with the first day.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Evaluation of cytotoxicity and mechanical properties of fluorapatite-45S5 bioactive glass nanocomposite

The purpose of this study was to fabricate and characterize nanocomposite powder from 45S5 bioactive glass/ fluorapatite. Nanocomposites containing 10, 15 and 20 wt.% of fluorapatite were synthesized by sol-gel method. XRD and FT-IR analyses were used to characterize and evaluate the produced nanocomposites. The results of XRD and FT-IR analysis indicated the successful synthesis of high purity...

full text

Clinical Applications of S53P4 Bioactive Glass in Bone Healing and Osteomyelitic Treatment: A Literature Review

Nowadays, S53P4 bioactive glass is indicated as a bone graft substitute in various clinical applications. This review provides an overview of the current published clinical results on indications such as craniofacial procedures, grafting of benign bone tumour defects, instrumental spondylodesis, and the treatment of osteomyelitis. Given the reported results that are based on examinations, such ...

full text

Cytotoxicity and Genotoxicity Evaluation of Fluorapatite/bioactive Glass Nanocomposite Foams With Two Various Weight Ratios as Bone Tissue Scaffold: an in vitro study

The optimization of biomaterials’ biodegradation rate similar to tissue regeneration, is one of the main goals of tissue engineering. However, the necessity to assess their possible toxicity is always considered. The aim of this study was cytotoxicity and genotoxicity evaluation of fluorapatite/bioactive glass (FA/BG) nanocomposite foams with two various weight ratios to determine the optimal c...

full text

Bioactive glass S53P4 as bone graft substitute in treatment of osteomyelitis.

Bioactive glass (BAG)-S53P4 is an osteoconductive bone substitute with proven antibacterial and bone bonding properties. In a multicentre study 11 patients with verified chronic osteomyelitis in the lower extremity and the spine were treated with BAG-S53P4 as a bone substitute. The cavitary bone defect and the surrounding of a spinal implant were filled with BAG-S53P4. The most common pathogen ...

full text

Preparation of nano bioactive glass and investigation of its properties in different volume of solution

Nano Bioactive glass material of the type CaO–P2O5–SiO2 was obtained by the sol-gel processing method at considerably lower temperatures than required for conventional melting methods. As a new modification, volume of solution was changed in order to investigate its effects on the properties of bioglass samples. The obtained material was characterized by X-ray powder diffraction (XRD), surface ...

full text

Preparation of nano bioactive glass and investigation of its properties in different volume of solution

Nano Bioactive glass material of the type CaO–P2O5–SiO2 was obtained by the sol-gel processing method at considerably lower temperatures than required for conventional melting methods. As a new modification, volume of solution was changed in order to investigate its effects on the properties of bioglass samples. The obtained material was characterized by X-ray powder diffraction (XRD), surface ...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 6  issue 3

pages  145- 156

publication date 2019-09-01

By following a journal you will be notified via email when a new issue of this journal is published.

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023